Publications

Mechanism for controlled assembly of transcriptional condensates by Aire

Huoh Y.-S.*, Zhang, Q.*, Torner, R., Baca, S. C., Arthanari, H., Hur, S. (2024) Nat. Immunol. *equal author contribution DOI: 10.1038/s41590-024-01922-w 

Death domain fold proteins in immune signaling and transcriptional regulation

Huoh, Y.-S., Hur, S. (2022). FEBS J. 289, 4082-4097. DOI: 10.1111/febs.15901

Dual functions of Aire multimerization in the transcriptional regulation of T cell tolerance

Huoh Y.-S., Wu, B. Park, S., Yang, D., Bansal, K. Greenwald, E., Wong, W.P., Mathis, D., Hur, S. (2020). Nat. Commun. 11, 1625. DOI: 10.1038/s41467-020-15448-w

Dominant-negative loss of function arises from a second, more frequent variant within the SAND domain of autoimmune regulator (AIRE) 

Abbott J.K.*, Huoh Y.-S.*, Reynolds P., Yu L., Rewers M., Reddy M., Anderson M.S., Hur S., Gelfand E.W. (2018). J. Autoimmun. 288, 114–120. *equal author contribution DOI: 10.1016/j.jaut.2017.10.010

Measuring Monomer-to-Filament Transition of MAVS as an In Vitro Activity Assay for RIG-I-Like Receptors  

Wu, B., Huoh, Y.-S., Hur, S. (2016). Methods Mol. Biol. 1390, 131–142. DOI: 10.1007/978-1-4939-3335-8_9

The Pellino E3 ubiquitin ligases recognize specific phosphothreonine-peptide sequences and have distinct substrate specificities  

Huoh, Y.-S., Ferguson, K.M. (2014). Biochemistry 53, 4946–4955. DOI: 10.1021/bi5005156

Local control of PtdIns4P signaling in the Golgi apparatus by Vps74 and Sac1 phosphoinositide phosphatase 

Wood, C.S., Hung, C.S., Huoh, Y.-S., Mousley, C.J., Stefan, C.J., Bankaitis, V., Ferguson, K.M., Burd, C.G. (2012). Mol. Biol. Cell 23, 2527–2536. DOI: 10.1091/mbc.E12-01-0077

Pellino proteins contain a cryptic FHA domain that mediates interaction with phosphorylated IRAK1

Lin, C.-C., Huoh, Y.-S., Schmitz, K.R., Jensen, L.E., Ferguson, K.M. (2008). Structure 16, 1806–1816. DOI: 10.1016/j.str.2008.09.011